Evaluasi Perbedaan Kadar Bilirubin Direk pada Individu dengan Riwayat Konsumsi Alkohol dan Tanpa Konsumsi Alkohol

Authors

  • Annisaturrahmah Himawan Universitas Islam Negeri Alauddin Makassar
  • Muhammad Habibullah Aminy Universitas Islam Al-Azhar
  • Lale Ajeng Khalifatun Wardani Universitas Islam Al-Azhar
  • Slamet Mardiyanto Rahayu Universitas Islam Al-Azhar
  • Fathurrahman Universitas Islam Al-Azhar

DOI:

https://doi.org/10.66294/njms.v3i4.172

Keywords:

Direct Bilirubin, Alcohol Consumption, Liver Function, Clinical Biochemistry

Abstract

Direct Bilirubin Is An Important Parameter In Assessing Liver Function, Particularly In Bilirubin Conjugation And Excretion Processes. Long-Term Alcohol Consumption Is Known To Cause Liver Dysfunction, Potentially Increasing Bilirubin Levels In The Blood. This Study Aimed To Evaluate Differences In Direct Bilirubin Levels Between Individuals With A History Of Alcohol Consumption And Non-Consumers. This Study Used An Analytical Observational Method With A Cross-Sectional Approach. The Sample Consisted Of Two Groups: Alcohol Consumers And Non-Consumers, Selected Using Purposive Sampling. Direct Bilirubin Levels Were Measured Using A Spectrophotometric Method. The Results Showed A Difference In Direct Bilirubin Levels Between The Two Groups, With Higher Levels Observed In Alcohol Consumers. Therefore, Alcohol Consumption May Affect Liver Function As Reflected By Increased Direct Bilirubin Levels.

Downloads

Download data is not yet available.

References

Burtis, C. A., & Bruns, D. E. (2019). Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics (8th ed.). Elsevier.

European Association for the Study of the Liver. (2018). EASL Clinical Practice Guidelines: Management of alcohol-related liver disease. Journal of Hepatology, 69(1), 154–181.

Friedman, L. S. (2018). Liver, biliary tract, and pancreas disorders. In Current Medical Diagnosis & Treatment. McGraw-Hill.

Ganong, W. F. (2018). Review of Medical Physiology (26th ed.). New York: McGraw-Hill.

Guyton, A. C., & Hall, J. E. (2016). Textbook of Medical Physiology (13th ed.). Philadelphia: Elsevier.

Henry, J. B. (2016). Clinical Diagnosis and Management by Laboratory Methods (23rd ed.). Elsevier.

Kementerian Kesehatan Republik Indonesia. (2023). Profil Kesehatan Indonesia Tahun 2022. Jakarta: Kemenkes RI.

Kumar, V., Abbas, A. K., & Aster, J. C. (2020). Robbins and Cotran Pathologic Basis of Disease (10th ed.). Elsevier.

Murray, R. K., Bender, D. A., Botham, K. M., Kennelly, P. J., Rodwell, V. W., & Weil, P. A. (2018). Harper’s Illustrated Biochemistry (31st ed.). New York: McGraw-Hill.

National Institute on Alcohol Abuse and Alcoholism. (2020). Alcohol and Liver Disease. Bethesda: NIH.

O’Shea, R. S., Dasarathy, S., & McCullough, A. J. (2019). Alcoholic liver disease. Hepatology, 51(1), 307–328.

Pratt, D. S., & Kaplan, M. M. (2017). Evaluation of abnormal liver-enzyme results. New England Journal of Medicine, 342(17), 1266–1271.

Rehm, J., et al. (2017). Global burden of disease and injury attributable to alcohol use. The Lancet, 389(10082), 2223–2233.

Sherlock, S., & Dooley, J. (2018). Diseases of the Liver and Biliary System (13th ed.). Oxford: Wiley-Blackwell.

Stickel, F., & Hampe, J. (2019). Genetic determinants of alcoholic liver disease. Gut, 61(10), 150–159.

Tietz, N. W. (2015). Clinical Guide to Laboratory Tests (4th ed.). Philadelphia: Saunders.

World Health Organization. (2021). Guidelines for Screening and Management of Alcohol Use Disorders. Geneva: WHO.

World Health Organization. (2022). Global Status Report on Alcohol and Health. Geneva: WHO.

Downloads

Published

2026-06-30

How to Cite

Annisaturrahmah Himawan, Muhammad Habibullah Aminy, Lale Ajeng Khalifatun Wardani, Slamet Mardiyanto Rahayu, & Fathurrahman. (2026). Evaluasi Perbedaan Kadar Bilirubin Direk pada Individu dengan Riwayat Konsumsi Alkohol dan Tanpa Konsumsi Alkohol. Nusadaya Journal of Multidiciplinary Studies, 3(4), 1–5. https://doi.org/10.66294/njms.v3i4.172

Most read articles by the same author(s)

<< < 1 2 3 4 5 6 7 8 9 10 > >>